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  • 标题:Cardio-Toxicity during chemotherapy: feasibility of new diagnostic approaches
  • 本地全文:下载
  • 作者:Fable Zustovich ; Mario Trivellato ; Renato Ceravolo
  • 期刊名称:Health
  • 印刷版ISSN:1949-4998
  • 电子版ISSN:1949-5005
  • 出版年度:2010
  • 卷号:2
  • 期号:4
  • 页码:376-380
  • DOI:10.4236/health.2010.24056
  • 出版社:Scientific Research Publishing
  • 摘要:Chemotherapy induced cardio-toxicity is a well known side effect of anticancer treatments, moreover the 70% of all tumors involve patients over 65 years-old, frequently with cardiac co- morbidity. We evaluated the feasibility of the application during chemotherapy administration of some of the most recent diagnostic techniques as 12-diagnostic leads telemetry, 7 days EKG monitoring device (R-Test Evolution 3R), blood level dosage of Brain Natriuretic Peptide (BNP) and Ischemia Modified Albumin (IMA). Some sub-clinical changes in the investigated parameters were found in patients undergoing chemotherapy, mostly containing fluorouracil, as shown in the following paper. Far from suggesting a widespread use of these methods during chemotherapy administration, we think that some more tools are needed to prevent cardiac toxicity in high-risk patients and some of what we studied may deserve further valuation in chemotherapy clinical trials.
  • 关键词:Cardio-Toxicity Diagnostic
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