摘要：Background Human brain activity in the gamma frequency range has been shown to be a correlate of numerous cognitive functions like attention, perception and memory access. More specifically, gamma activity has been found to be enhanced when stimuli are stored in or match with short-term memory (STM). We tested the hypothesis that gamma activity is also evoked when stimuli match representations in long-term-memory (LTM). EEG was recorded from 13 subjects performing a choice reaction task. Visual stimuli were either known real-world objects with a memory representation or novel configurations never seen before. Results All stimuli evoked an early gamma response which was maximal over occipital electrodes. This evoked gamma activity was significantly larger for items that matched memory templates. Conclusions Therefore, we argue that gamma activity results from the feedback from memory into perception systems. This assumption seems to be true for STM as well as LTM.
