摘要：The use of health-related quality of life (HRQOL) measurements has been increased progressively in health surveys. These measurements document the functional and psychosocial outcomes of health conditions and complement clinical indicators to provide a comprehensive description of individuals and populations' health. The Pediatric Quality of Life Inventory™ (PedsQL™) is a promising instrument with age-appropriate versions. The objective of the current paper was to evaluate the psychometric properties of the PedsQL™ 3.0 Cancer Module cross-culturally adapted for use in Brazil. A cross-sectional study was developed with 190 Brazilian families of individuals from 2 to 18 years of age, of both genders, with cancer in various phases of treatment or control. Subjects were recruited by means of convenience samples from the Pediatric Hematology/Oncology Centers at two public hospitals. 'In-treatment' status was defined as individuals who were receiving medical care to induce remission. 'Off-treatment' status was defined as individuals for whom all therapy was completed for a period of at least one month. Reliability was determined through test-retest reliability and internal consistency. The validity of the Cancer Module was determined through discriminant and convergent validity. Correlations between the scores obtained by the children/adolescents with cancer and their guardians were assessed. Test-retest reliability demonstrated good correlation (0.69–0.90 for children/adolescents; 0.71–0.93 for guardians) and adequate agreement of the items (0.26–0.85 for children/adolescents; 0.25–0.87 for guardians). Internal consistency demonstrated adequate indices in comparisons between groups (α = 0.78–0.80 for children and adolescents; 0.68–0.88 for guardians). The 'pain and hurt', 'nausea', 'procedural anxiety' and 'treatment anxiety' subscales proved capable of distinguishing the groups of children in treatment and off treatment (p < 0.05). Positive significant correlations were observed between the scores of the PedsQL™ 3.0 Cancer Module and the PedsQL™ 4.0 Generic Core scales. Weak correlations were found between the reports of the children and those of the guardians. The Brazilian version of the PedsQL™ 3.0 Cancer Module exhibited good measurement properties regarding reproducibility and construct validity.
关键词：Life Inventory ; Pediatric Cancer Patient ; Pediatric Quality ; Cancer Module ; Generic Core Scale
