摘要：Haematotoxic effects following administration of kerosene and Petrol-contaminated diets were investigated in male and female albino rats. Haematological parameters namely haemoglobin (Hb), Packed Cell Volume (PCV), White Blood Cell Counts (WBC) and differentials were used to assess the effect of kerosene and petrol-contaminated diets on rats. LD50 values of kerosene and petrol were obtained at levels of 212 and 128 mL kg-1 of feed respectively for 12 weeks. Long term exposure of the animals to kerosene and petrol-contaminated diets caused a significant decrease (p≤0.05) in PCV and Hb indicating an anaemic condition. Male and female rats fed diets contaminated with kerosene and petrol showed a significant decrease (p≤0.05) in the WBC counts. Result of the differential count showed a significant increase (p≤0.05) in neutrophils of male and female rats fed diets contaminated with kerosene and petrol while lymphocytes, antibody forming leucocytes decreased significantly (p≤0.05) among rats fed diets contaminated with kerosene and petrol indicating a response to stress and susceptibility of the animals to infection. Long term exposure of rats to kerosene and petrol-contaminated diets induced anaemia as observed in this study.
