摘要：Nasopharyngeal carcinoma is the most common malignant tumour of the nasopharynx with lymphoepithelioma being a more common subtype. It presents often in younger age groups and shows a definite association with Epstein-Barr virus. In our case report, the patient presented with nasal obstruction and left cervical lymphnode mass. There was involvement of the skull base, with extension to cavernous sinus, epidural and intraspinal space. The patient was given radiotherapy following which the neck mass subsided completely. The primary treatment of nasopharyngeal carcinoma is high dose radiation therapy, both for the primary tumour site and the neck. Surgery is indicated in case of nodes that do not regress after radiation or that reappear following complete clinical response. Neoadjuvant chemotherapy is used to shrink the tumours to make them more definitely treatable with radiation . An effective immunologically based approach in future, with certain antiEBV antibodies associated with improved prognosis, offers good hope.
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