摘要：Homocysteine has been identified as a risk factor for Coronary artery disease. High levels have been implicated in atherosclerosis, cerebro vascular disease and peripheral vascular disease. Along with genetic causes of hyperhomocysteinaemia, others like dietary deficiencies, cigarette smoking, and physical inactivity also cause hyperhomocysteinaemia. Few randomized controlled trials have been conducted where supplementation with Folic acid, vit. B12, and Trimethylglycine bring about reduction in plasma Homocysteine levels.
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