标题：Thematic review series: Systems Biology Approaches to Metabolic and Cardiovascular Disorders. Approaches to lipid metabolism gene identification and characterization in the postgenomic era
出版社：American Society for Biochemistry and Molecular Biology
摘要：The availability of genomic resources has already had a tremendousimpact on biomedical research. In this review, we describe howwhole genome sequence and high-throughput functional genomicsprojects have facilitated the identification and characterizationof important genes in lipid metabolism and disease. We reviewkey approaches and lipid genes identified in the first yearsof this century and discuss how genomic resources are likelyto streamline gene identification and functional characterizationin the future.Supplementary key words comparative genomics • positional cloning • functional genomics • gene-trap mutagenesis • ethylnitrosourea mutagenesis
