摘要：Aim: The aim was to study prescription-drug use in pregnant women in the department of the Aube. Method: We used the data-base of the general scheme of French health insurance (régime général de l’assurance maladie) in order to obtain all reimbursed drug prescriptions for March 2000. Results: The incidence of prescription-drug use in this cohort of women was 81.78 per 100 persons month. Among the 1,313 pregnant women who were reimbursed for at least one medication, 1.7% took a prescription drug which was absolutely contra-indicated during pregnancy and 3.9% received one which was relatively contra-indicated during pregnancy. More than half of these cases involved topical prescription drugs. The most frequently prescribed contra-indicated drugs were non-steroid anti-inflammatory drugs (absolutely contra-indicated) and aminosides (relatively contra-indicated). Conclusion: The authors insist on the potential danger of topical drug use in pregnant women, a fact which is undoubtedly ignored by patients and possibly by druggists and prescribing physicians as well.
