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  • 标题:Diagnosis of fetal alcohol spectrum disorder (FASD): fatty acid ethyl esters and neonatal hair analysis
  • 本地全文:下载
  • 作者:Daniela L. Caprara ; Julia Klein ; Gideon Koren
  • 期刊名称:Annali dell'Istituto Superiore di Sanita
  • 印刷版ISSN:0021-2571
  • 出版年度:2006
  • 卷号:42
  • 期号:01
  • 页码:39-45
  • 出版社:Editrice Kurtis Srl
  • 摘要:Measuring levels of fatty acid ethyl esters (FAEE) in hair has been recently shown to discrimi­nate between adult heavy and non-drinkers. Here, we review the potential of neonatal FAEE measurement in detecting infants exposed to alcohol in utero by outlining current progress in the development of a neo­natal hair test for the diagnosis of fetal alcohol spectrum disorder (FASD). Developing a reproducible, ac­curate and predictable hair test for FAEE measurements in neonatal hair may prove to be a powerful tool in the detection of in utero alcohol exposure which is needed for the diagnosis of FASD. Such a neonatal hair test can revolutionize current FASD diagnostic methodology by providing early diagnosis, allowing intervention and treatment at stages where the adverse effects of alcohol can still be mitigated.
  • 关键词:fetal alcohol spectrum disorder, in utero alcohol exposure, neonatal hair testing, alcohol biomarkers, fatty acid ethyl esters.
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