摘要：This study has been addressed to the non neoplastic effects observed in experimental animals
exposed to the ELF magnetic fields exposure, giving particular attention to the large and comprehensive
data of the two-year NTP (National Toxicology Program) studies. The statistical analysis of non
neoplastic incidences, whenever not presented by the study authors, has been carried out in the present
study. Only the effects coherently emerging for both the animal genders have been considered; gender
specific effects have obviously been separately analysed. The trend analysis has been carried out over the
4 exposure levels (0, 2, 200 μT, and 1000 μT -microTesla) and on the first 3 ones. For 28 dose-response
relationships, non neoplastic effects significantly emerged (6 for hyperplasia, 4 for cyst, 4 for inflammation,
3 for focus, 3 for atrophy, 2 for cellular infiltration, and 1 for each of other 6 effects). This number
is much higher than the one of neoplastic effects indicated by the NTP as significant. For many of these
dose-response relationships, the trend was significant only over the first 3 treatment levels (excluding the
highest one, 1000 μT/1 mT), in agreement with the results of some other studies indicating a response
reduction, or even a possible anticarcinogenic effects, at considerably high exposures (mT range). The
obtained results suggest a complex effect modulation pattern.
关键词：ELF, electromagnetic fields, animal experiments, non neoplastic effects.
