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文章基本信息

  • 标题:Decomposition of neuronal assembly activity via empirical de-Poissonization
  • 作者:Werner Ehm ; Benjamin Staude ; Stefan Rotter
  • 期刊名称:Electronic Journal of Statistics
  • 印刷版ISSN:1935-7524
  • 出版年度:2007
  • 卷号:1
  • 页码:473-495
  • 出版社:Institute of Mathematical Statistics
  • 摘要:Consider a compound Poisson process with jump measure $nu$ supported by finitely many positive integers. We propose a method for estimating $nu$ from a single, equidistantly sampled trajectory and develop associated statistical procedures. The problem is motivated by the question whether nerve cells in the brain exhibit higher-order interactions in their firing patterns. According to the neuronal assembly hypothesis (Hebb, 1949), synchronization of action potentials across neurons of different groups is considered a signature of assembly activity, but it was found notoriously difficult to demonstrate it in recordings of neuronal activity. Our approach based on a compound Poisson model allows to detect the presence of joint spike events of any order using only population spike count samples, thus bypassing both the ``curse of dimensionality'' and the difficulties of simultaneously recording the spike trains of many single units.
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