期刊名称：Journal of Indian Association for Child and Adolescent Mental Health
电子版ISSN：0973-1342
出版年度：2006
卷号：2
期号：04
页码：100-107
出版社：Indian Association for Child and Adolescent Mental Health
摘要：Aim: To study the prevalence of psychiatric diagnosis and psychopathology in adolescent
offspring of parents with panic disorder, depression and normal controls
Methods: Adolescent offspring (11-16 years) of parents with a diagnosis of panic disorder and
major depression, and normal controls were interviewed using Missouri Assessment of Genetics
Interview for Children (MAGIC), Scale for Childhood Anxiety Related Emotional Disorders
(SCARED), Strengths and Difficulties Questionnaire (SDQ) and the Children’s Global
Assessment Scale (CGAS).
Results: Thirty three adolescent offspring of parents with panic disorder, 47 of parents with
unipolar depression, and 37 of normal controls were interviewed. A diagnosis of simple phobia
was made significantly more often in adolescent offspring of parents with panic disorder
compared to controls. Adolescent offspring of parents with depression had significantly higher
rates of panic disorder and depression compared to controls. The total scores on SCARED and
SDQ were significantly higher among the offspring of parents with panic disorder and
depression compared to controls and the former were more functionally impaired.
Conclusions: There was an excess prevalence of psychopathology and a greater degree of
functional impairment in adolescent offspring of parents with panic disorder and depression
compared to adolescent offspring of normal controls.
