Breast tumours showing pure myoepithelial or epithelial myoepithelial differentiation are rare. Adenomyoepithelioma (AME) is defined as proliferation of both epithelial and myoepithelial elements. It is characterized by biphasic morphologic population, epithelial and myoepithelial with predominantly solid, clear cell myoepithelial proliferation and luminal epithelial element. When the glandular elements predominate with glands lined by two row of cells, it is termed as Adenomyoepithelial adenosis (AA) where inner luminal layer of apocrine cells and outer row of clear cells is present. This adenosis is known to be either preceding to AME or is an integral part of it.

We report a rare case of Adenomyoepithelioma (AME) of breast in association with Adenomyoepithelial adenosis (AA) in a 35 year old female