摘要:This study investigates the possible protective
effect of dietary supplements and their efficacy in rat experimental 6 months
intoxication with 2,4-dichloro-phenoxyacetic acid herbicide (2,4-D). The
protecting tested agents were: metaspar (M), a drug containing
methionine, aspartic acid, B1, B6 and PP vitamins and eurovita (E),.a mix
of multiminerals and multivitamins. All tested substances were administered in
food, twice a week, dissolved in sunflower oil. Animals 10/group were fed
respectively with: standard food (control), equivalent vehicle (vehicle
control), toxic (2,4-D), metaspar protected group (2,4-D+M) and
eurovita protected group (2,4-D+E). After 6 months they were sacrificed,
blood and liver were analyzed with standard methods and commercial kits for
total and reduced glutathione, erythrocyte superoxide dismutase (SOD) activity
and serum thiobarbiuric acid reactive substances (TBARS) (lipoperoxides). The
results showed the enhancement of antioxidant defense in protected groups,
without clear-cut differences between the two tested compounds