首页    期刊浏览 2024年11月29日 星期五
登录注册

文章基本信息

  • 标题:Antioxidant status in protected experimental herbicide intoxication
  • 本地全文:下载
  • 作者:Felicia,Gradinariu ; Al. Maftei ; Doina Popa
  • 期刊名称:Journal of Preventive Medicine
  • 印刷版ISSN:1582-5388
  • 出版年度:2007
  • 卷号:15
  • 出版社:Institute of Public Health, Iasi
  • 摘要:This study investigates the possible protective effect of dietary supplements and their efficacy in rat experimental 6 months intoxication with 2,4-dichloro-phenoxyacetic acid herbicide (2,4-D). The protecting tested agents were: metaspar (M), a drug containing methionine, aspartic acid, B1, B6 and PP vitamins and eurovita (E),.a mix of multiminerals and multivitamins. All tested substances were administered in food, twice a week, dissolved in sunflower oil. Animals 10/group were fed respectively with: standard food (control), equivalent vehicle (vehicle control), toxic (2,4-D), metaspar protected group (2,4-D+M) and eurovita protected group (2,4-D+E). After 6 months they were sacrificed, blood and liver were analyzed with standard methods and commercial kits for total and reduced glutathione, erythrocyte superoxide dismutase (SOD) activity and serum thiobarbiuric acid reactive substances (TBARS) (lipoperoxides). The results showed the enhancement of antioxidant defense in protected groups, without clear-cut differences between the two tested compounds
  • 关键词:2,4-dichlorophenoxyacetic acid, protection, amino acid, lipid peroxidation, herbicide
国家哲学社会科学文献中心版权所有