摘要:The aim of
this study was to estimate the proportion of the MRSA strains in community by analysis of the pharyngeal
swabs from children with acute and chronic pharyngitis assisted in medical
ambulatory units. Material and
methods. A number of 128 S.aureus
strains isolated during the period of 2002-2004 from 1782 children were tested
concerning their susceptibility to oxacillin. All S.aureus strains with oxacillin
inhibition zones diameter <13 mm were tested concerning the Minimal
Inhibitory Concentrations (MICs) by agar dilution method, recommended by
National Committee for Clinical Laboratory Standards (NCCLS). The strains with
MICs ≥
4 μg/ml to oxacillin were
considered methicillin -resistant Staphylococcus aureus (MRSA). Results. Among the 128 S.aureus strains isolated from
community, a number of 14 strains had a zone of inhibition <13 mm diameter
and 7 (5.4 %) strains had MICs ≥ 4 μg/ml, being MRSA. Only one
strain (3.1%) from a number of 32 strains isolated in the year of 2002 was MRSA.
From a number of 32 strains isolated in 2003, only 2 (6.2 %) were MRSA and from
62 strains isolated in the year of 2004, 4 (6.4 %) were MRSA. The MICs were ≥ 4
μg/ml for one strain, 8 μg/ml for 4 strains and 16
μg/ml for 2 strains. Conclusions. A
number of 7 strains of 128 S. aureus
strains were MRSA (5.4%). The community isolates which are generally susceptible
to multiple antibiotics are in contrast to the typical,
multiple-drug-resistant hospital MRSA ones. Although the percentage of the
community - MRSA strains in our area is low, our data pointed out their presence
in the community and underlined the
importance of MRSA strains from community as possible sources for
hospital infections.
关键词:S. aureus, strains,
methicillin-resistant, children, community