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  • 标题:Numerical Simulation Of Electrokinetic Flow In Microfluidic Chips.
  • 本地全文:下载
  • 作者:Fabio A. Guarnieri ; Pablo A. Kler ; Claudio L. A. Berli
  • 期刊名称:Mecánica Computacional
  • 印刷版ISSN:2591-3522
  • 出版年度:2006
  • 卷号:XXV
  • 期号:28
  • 页码:2573-2584
  • 出版社:CIMEC-INTEC-CONICET-UNL
  • 摘要:Microfluidic chips are miniaturized analytical devices used in chemical, biological and
    medical applications. In most cases, fluids are conducted through microchannels by applying electric
    potentials and/or pressure gradients. This growing lab-on-a-chip technology requires numerical
    simulations to assist the design, control and optimization of analytical manipulations. The present
    work deals with FEM-based calculations of the dynamics of electrolyte solutions in cross-shaped
    microchannels, where the flow is driven by the action of external electric fields. A theoretical
    modeling of electrokinetic and transport phenomena in the system is carried out in the framework of
    continuum fluid mechanics. Calculations ground on conservation equations of mass, momentum and
    electrical charge, considering effects in three dimensions. Operations normally performed in analytical
    systems are discussed, such as loading, focusing, and injection of samples. Numerical simulations
    carried out in this work can be a valuable tool to control and optimize practical manipulations in
    microfluidic chips.
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