Grid Computing has been identified as an important new technology in scientific and engineering fields as well as many commercial and industrial enterprises. Grid Computing is a form of distributed computing that involves coordination and sharing of computing application, data storage or network resources across dynamic and geographically dispersed organizations. In short, it involves virtualizing computing resources. Grids provide an infrastructure that allows for flexible, secure, coordinated resource sharing among dynamic collections of individuals, resources, and organizations. In this paper we develop an application framework for remote data monitoring in Power Distribution System by using Grid Computing. Using this framework it is easy to monitor and control the parameters such as voltage, load, frequency and power factor in electrical power distribution system. By monitoring all these parameters the line loss can be predicted and can be reduced so that the revenue will automatically be increased in the Power Distribution system by using this Application framework.