标题：La malattia di Creutzfeldt-Jakob e le altre forme umane di encefalopatie spongiformi trasmissibili in Italia: uno studio di mortalità condotto su fonti diverse
摘要：Creutzfeldt-Jakob Disease (CJD) is a rare pathology (about 1 case per million) but
it has a great importance for Public Health; the Italian National CJD register has been established in the Istituto
Superiore di Sanità (ISS) since 1993, and epidemiological studies on CJD have been carried out as well. This
paper reports a mortality study carried out comparing and integrating data from the two available sources: the
National CJD Register and the Italian Data Base on Mortality, processed by the ISS Statistics Unit, on the data
collected by the Italian Census Bureau (ISTAT). The study allowed to estimate: the underreporting of CJD
mortality to both sources, the misclassification of ISTATdata and the integrated mortality rates from CJD in
Italy: 1.58 per million persons aged 25 or more, average rate during the period 1993-1999.
关键词：Creutzfeldt-Jakob disease, mortality, data sources, surveillance, record linkage.
