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  • 标题:Discriminant analysis to study trace elements in biomonitoring: an application on neurode-generative diseases
  • 本地全文:下载
  • 作者:Anna Pino ; Sonia Brescianini ; Cristina D'Ippolito
  • 期刊名称:Annali dell'Istituto Superiore di Sanita
  • 印刷版ISSN:0021-2571
  • 出版年度:2005
  • 卷号:41
  • 期号:02
  • 页码:223-228
  • 出版社:Editrice Kurtis Srl
  • 摘要:Quantification of 26 elements was performed in blood of patients affected by neurodegenerative pathologies, i.e., Alzheimer’s disease (AD), Parkinson’s disease (PD) and multiple sclerosis (MS), and of a control group to study the potential role of blood elements as markers for the different neurodegenerations. A multivariate discriminant analysis (stepwise method) was applied to determine the best set of variables to discriminate among subjects with different health status. Preliminary results show three classification functions of seven elements, namely Ca, Co, Cu, Fe, Ni, Pb and Zr.
  • 关键词:neurodegenerative diseases, Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, trace elements, discriminant analysis.
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