摘要：The repellent and anti-feeding effect of garlic oil was
evaluated in laboratory conditions against the bite of Phlebotomus papatasi females. The effectiveness was
evaluated by two different laboratory procedures: (i) topical application of garlic oil on five human volunteers,
using the “standard cage test”, and (ii) feeding sandflies on artificial membranes treated with the compound.
Garlic oil showed a significant protection by topical application on the skin of volunteers, being the protection
97% and 40%, respectively at 1% and 0.005% dilution. Garlic oil showed also an anti-feeding effect when
tested on the artificial membrane feeding apparatus; the anti-feeding effect was dose dependent, being 100%
at 1%. The results of the present study confirm previous observations on the repellent effect of garlic oil
against haematophagous arthropods.
关键词：garlic oil, sandflies, Leishmania vectors, human volunteers, protection, control.
