摘要：Superficial Candida infections are very common throughout the world. Clotrimazole may be administered topically in the treatment of superficial candidiasis. We have tested the anti-fungal activity of eight 1% clotrimazole pharmaceutics (solutions, suspensions, ointments), against 3 Candida strains ( C. albicans , C. tropicalis , Candida spp.), using the diffusion method of susceptibility testing to anti-microbial drugs. In order to compare the anti‑fungal activity of the 3 groups of pharmaceutics (solutions/ suspensions/ ointments) the ANOVA statistical test was performed. The activity of clotrimazole significantly decreased from solutions to suspensions and ointments. There were no significant differences in anti- Candida activity among the same type of pharmaceutical form; excepting the activity of ointments against C. albicans . Anti-fungal activity of clotrimazole is better expressed in solutions, comparing with suspensions and ointments.
