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  • 标题:Adverse health effects associated with methemoglobinemia in children
  • 本地全文:下载
  • 作者:Gabriela Mancaş, MarietaVasilov ; Gabriela Albu
  • 期刊名称:Journal of Preventive Medicine
  • 印刷版ISSN:1582-5388
  • 出版年度:2002
  • 卷号:10
  • 期号:1
  • 出版社:Institute of Public Health, Iasi
  • 摘要:In order to point out some health effects associated with methemoglobinemia in children , we investigated a battery of oxidative and antioxidant defence bioindicators ( methemoglobin , reduced glutathione , lipid peroxides and glutathione peroxidase ) in 336 children aged 0-3 years living in eight rural localities within three districts , confirmed as high risk territories for nitrate exposure in drinking water . The results showed significant increased lipid peroxides levels in the children exposed to nitrates vs. unexposed group , as a possible early reversible effect of exposure . The investigation also highlighted significant differences of the biochemical changes pattern in 0-3 year aged children at two levels (moderate and high ) of nitrate concentrations in drinking water .
  • 关键词:style="mso-bidi-font-weight: normal"> epidemiological study , bioindicators , methemoglobin , lipid peroxides , glutathione
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