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  • 标题:Reactivators of cholinesterase activity in methylparathion exposed rats
  • 本地全文:下载
  • 作者:Irina Popovici ; Didona Ungureanu ; Cătălina Elena Lupuşoru
  • 期刊名称:Journal of Preventive Medicine
  • 印刷版ISSN:1582-5388
  • 出版年度:2002
  • 卷号:10
  • 期号:2
  • 出版社:Institute of Public Health, Iasi
  • 摘要:The cholinesterase activity and the biochemical antioxidant parameters in the blood of rats exposed to an organophosphate pesticide, methylparathion , in dose of 1/20 from LD50, and subsequently treated with quaternary ammonium iodides from Mannich bases oximes have been determined. Our research on the reactivator effects of both original synthesized substances named Q1 and Q2, compared with toxogonin , showed their reactivator capacity according with cholinesterase activity and the biochemical effects caused by the membrane oxidative stress
  • 关键词: cholinesterase, methylparathion , toxogonin , Mannich bases oxime , oxidative stress, superoxide dismutase , catalase , glutathione peroxidase
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