摘要：The aims of this study were to evaluate the influence of the herbicide atrazine on peripheral mononuclear cells on occupationally exposed individuals in terms of their possible DNA – damage effect and to determine whether p53 protein can serve as a biomarker for this exposure or not . 19 workers employed by “ Chimcomplex ” Company – Borzesti ( Romania ) in the atrazine production unit were examined and p53 immunocytochemistry was performed . The results showed that 68.4% of the workers were positive for p53 protein and these data were interpreted as a proof indicating that immunocytochemical detection of the p53 protein expression is a feasible means for monitoring atrazine exposure .
