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  • 标题:Antioxidant enzyme levels in reactive arthritis and rheumatoid polyarthritis
  • 本地全文:下载
  • 作者:Irina Popovici ; Elena Rezuş ; Gabriela Mancaş
  • 期刊名称:Journal of Preventive Medicine
  • 印刷版ISSN:1582-5388
  • 出版年度:2001
  • 卷号:9
  • 期号:2
  • 出版社:Institute of Public Health, Iasi
  • 摘要:This study is based on the comparative analysis of 38 patients with reactive arthritis defined by Amor criteria, a group of 33 patients with rheumatoid polyarthritis and 50 healthy controls. Antioxidant systems (glutathione peroxidase, superoxide dismutase, catalase) were investigated in inflammation consecutive to immune and infectious syndromes. Our study showed that reactive arthritis and rheumatoid arthritis is associated with enhanced oxidative stress. The lower levels of natural blood antioxidant enzyme, were related to severe forms of disease. The investigation of oxidative metabolism lies at the basis of antioxidant therapy that could influence the natural course of reactive arthritis and polyarthritis.
  • 关键词:reactive arthritis, rheumatoid poyarthritis, oxidative stress, oxygen free radicals, catalase, glutathione peroxidase, superoxide dismutase
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