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  • 标题:EFFECTS OF EXPOSURE TO FLAX DUST IN POLISH FARMERS: WORK-RELATED SYMPTOMS AND IMMUNOLOGIC RESPONSE TO MICROBIAL ANTIGENS ASSOCIATED WITH DUST
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  • 作者:&]HVáDZD6NyUVND ; Barbara Mackiewicz ; Jacek Dutkiewicz
  • 期刊名称:Annals of Agricultural and Environmental Medicine
  • 印刷版ISSN:1232-1966
  • 电子版ISSN:1898-2263
  • 出版年度:2000
  • 卷号:7
  • 期号:02
  • 出版社:Institute of Agricultural Medicine in Lublin
  • 摘要:Medical examinations were performed in a group of 51 Polish farmers heavily exposed to flax dust during harvesting and scutching (threshing) and in a group of 50 healthy urban dwellers not exposed to organic dusts (controls). The examinations included: interview concerning the occurrence of respiratory disorders and work-related symptoms, physical examination, X-ray examination of chest, lung function tests, oxymetric examinations, determination of the concentration of cytokines (IL-.,/-6, 71).  LQEORRGVHUXPDQGDOOHUJRORJLFDOWHVWVZLWKPLFURELDODQWLJHQVDVVRFLDWHGZLWK organic dust, comprising: skin prick test with 4 antigens, agar-gel precipitation test with 12 antigens and test for specific inhibition of leukocyte migration with 4 antigens. As many as 32 farmers (62.7%) reported the occurrence of work-related symptoms during harvesting, transporting and scutching of flax. The most common complaint was general weakness reported by 15 farmers (29.4%), followed by headache reported by 14 (27.5%), blocking of the nose - by 11 (21.6%), dry cough, shivering, and eyes itching - each by 10 (19.8%), chest tightness and hoarseness - each by 9 (17.6%). No control subjects reported these work-related symptoms. The mean spirometric values in the examined group of farmers were within a normal range and did not show a significant post-shift decline. In contrast, a significant post-shift decline of oxymetric values was found among flax farmers.The farmers showed a frequency of the positive early skin reactions to environmental allergens in the range of 0–19.6%, a frequency of positive precipitin reactions in a range of 0–56.9.%, and frequency of positive reactions of leukocyte migration inhibition in a range of 7.8–21.6%. The members of the control group responded to the majority of allergens with a significantly lower frequency of positive results compared to the farmers. Elevated concentrations of IL-.DQG,/-6, but QRW71). were found in blood sera of flax farmers. In conclusion, farmers engaged in harvesting and scutching of flax represent a group of elevated professional risk because of high incidence of work-related symptoms and high frequency of allergic reactions to bacteria and fungi associated with organic dust.
  • 关键词:farmers, flax, harvesting, scutching, organic dust, occupational exposure, health effects, work-related symptoms, allergy, microbial antigens, cytokines.
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