Amyloidosis is a heterogeneous group of disorders affecting a single-or multiple-organ system
and presents as generalized or localized disease. Which can be primary or secondary. Localized
amyloidosis affects organs like urinary bladder, lung, larynx, skin and tongue, producing detectable
nodular masses which are clinically suspected as malignancy. A case of primary amyloidosis
of the urinary bladder is reported. This is a rare clinical entity and is of interest to the
urologist because it is usually confused with carcinoma clinically and cystoscopically and histological
examination is a must for definite diagnosis and proper management