Diabetes mellitus is a chronic disease of metabolic dys-regulation involving the abnormal metabolism
of glucose. Diabetes has a significant impact on the healthcare costs of the Western world. Nearly all patients
with diabetes eventually develop cutaneous manifestations of the disease. Cutaneous signs of the disease can
heighten the suspicions of a physician regarding the diagnosis of diabetes. This article will focus on the clinical
features, pathogenesis and modern treatment modalities of the various dermatologic manifestations of the
disease ranging from the more benign granuloma annulare to the more sinister diabetic ulcer.