OBJECTIVE: Our objective was to describe primary care patients' perceptions of informed and shared decision making about cancer screening tests in a diverse sample. METHODS: We administered a 33-item survey to 467 women and 257 men aged 50 years and older from seven practices in a family medicine practice-based research network. We used ordered logistic regression to assess the relationship between gender, race, education, marital status, and self-rated health with measures of patient-centered care relating to cancer screening tests, controlling for practice site. RESULTS: Men had greater odds than women of reporting they did not know the benefits of cancer screening (1.46, 95% CI=1.08, 1.99). Compared to white respondents, black respondents reported greater odds of not knowing the benefits (1.70, 95% CI=1.23, 2.36) and risks (1.38, 95% CI=1.00, 1.90) of cancer screening, of not making informed choices (1.50, 95% CI=1.09, 2.07), and that their doctor did not give them some control over their cancer screening tests (1.57, 95% CI=1.12, 2.20). Low education level was also associated with lower perceptions of informed decision making. CONCLUSIONS: Patients with male sex, non-white race, and low education level reported more uncertainty about cancer screening tests and less patient-centered care