By comparing the similarities between SDN (Supply and Demand Network with multifunctional and opening characteristics for enterprise) and natural ecosystem, the ecological characteristics of SDN enterprise are summarized in this article. The relationship among biological species groups in the natural ecosystem is used to describe the relationships of SDN enterprise in the collaborative innovation, and the collaborative innovation model among SDN enterprises based on the biology is generalized. In addition, four kinds of collaborative innovation oriented SDN enterprise ecological collaborative models are expounded respectively in detail.