The role of oil and gas exploration and other natural resources in the economic development of a country cannot be over emphasized. Unfortunately, in most oil producing countries women have not benefited from oil and gas exploration. This study therefore seeks to explore the effects of the oil find in Ghana on the livelihood of women in the catchment area of Cape Three Points. Purposive sampling was used to select two hundred and forty respondents who were interviewed in two communities at Cape Three Points about their anticipated challenges and prospects in the wake of the oil find. Results indicate that more than half of the respondents perceive a decrease in fish catch, loss of jobs for husbands and reduction in income levels. It is recommended that in order for women to take advantage of the oil find, there is the need to create alternative livelihoods such as access to finance; capacity building; training and development; and technical services for women in the catchment area.