The study investigated the possible impact of National Economic Empowerment and Development Strategy (NEEDS) on human development in Nigeria. NEEDS is a home-groomed economic and social package focused on fighting poverty and enthroning a people-centered developmental programmes. The paper evaluates each of the major thrusts of NEEDS by highlighting their respective demands for new patterns of human development. Also, collaborative and interactive model of human development is presented. The paper highlights three critical core areas that can enthrone the success of NEEDS for sustainable development. These are evangelistic development of indigenous professionals by providing needed supports in terms of training and development, infrastructural facilities and finance, enforcing the practice of business and social ethics after effective mobilization of the people psychic with the values reorientation component of NEEDS, and applying strict and swift sanctions on violations of social and economic ethics to serve as deterrent for others. It is expected therefore that through effective and efficient implementation, NEEDS will serve as a useful strategy and tool for economic development of Human resources.