期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2003
卷号：100
期号：1
页码：330-335
DOI：10.1073/pnas.222681699
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Amyloid {beta}-protein (A{beta}) is linked to neuronal injury and death in Alzheimer's disease (AD). Of particular relevance for elucidating the role of A{beta} in AD is new evidence that oligomeric forms of A{beta} are potent neurotoxins that play a major role in neurodegeneration and the strong association of the 42-residue form of A{beta
