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  • 标题:Proteomic analysis identifies that 14-3-3ζ interacts with β-catenin and facilitates its activation by Akt
  • 本地全文:下载
  • 作者:Qiang Tian ; Megan C. Feetham ; W. Andy Tao
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:2004
  • 卷号:101
  • 期号:43
  • 页码:15370-15375
  • DOI:10.1073/pnas.0406499101
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:{beta}-Catenin is a central effector of Wnt signaling in embryonic and stem cell development and in tumorigenesis. Here, through a mass spectrometric analysis of a {beta}-catenin protein complex, we identified 12 proteins as putative {beta}-catenin interactors. We show that one of them, 14-3-3{zeta
  • 关键词:stem cells
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