期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1991
卷号：88
期号：7
页码：2697-2701
DOI：10.1073/pnas.88.7.2697
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：We describe a Xenopus mRNA, Xrel1, that is related to the avian protooncogene c-rel, the embryonic pattern gene dorsal of Drosophila, and the mammalian transcription factor NK-kappa B/KBF1. The sequence of Xrel1 is homologous to the other rel-related proteins in the large amino-terminal region that defines this class of transcriptional regulators, but the carboxyl-terminal part of the protein is quite different. Xrel1 mRNA is present throughout oogenesis and during early embryogenesis at 4 x 10(5) transcripts per oocyte or embryo. Xrel1 transcripts are present in all of the dissected parts of early embryos that we have examined. They are enriched in the animal hemisphere compared to the vegetal hemisphere of oocytes and blastulae.
