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  • 标题:The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex
  • 本地全文:下载
  • 作者:H Lu ; O Flores ; R Weinmann
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1991
  • 卷号:88
  • 期号:22
  • 页码:10004-10008
  • DOI:10.1073/pnas.88.22.10004
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The two forms of RNA polymerase II that exist in vivo, phosphorylated (IIO) and nonphosphorylated (IIA), were purified to apparent homogeneity from HeLa cells. The nonphosphorylated form preferentially binds to the preinitiation complex. RNA polymerase II in the complex was converted by a cellular protein kinase to the phosphorylated form.
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