期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1982
卷号：79
期号：10
页码：3176-3178
DOI：10.1073/pnas.79.10.3176
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A new structural model is advanced to account for the specialized "catch" contraction of molluscan smooth muscles. The myosin of the thick filaments of these muscles is pictured as comprising a single layer of molecules whose assembly and activity are controlled by the underlying core of paramyosin. This organization differs from that in other muscles in which the myosin is grouped into bundles. The catch state--in which the lifetime of the actin-myosin linkage is extended--would depend directly on this special organization that allows an interaction of the entire rod region of myosin with the paramyosin core. This interaction might be modulated by phosphorylation of paramyosin.
