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  • 标题:Stimulation of Xenopus oocyte protein synthesis by microinjected adenovirus RNA
  • 本地全文:下载
  • 作者:J D Richter ; N C Jones ; L D Smith
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1982
  • 卷号:79
  • 期号:12
  • 页码:3789-3793
  • DOI:10.1073/pnas.79.12.3789
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:The ability of injected heterologous mRNAs to compete with endogenous mRNAs in Xenopus oocytes was assayed. In confirmation of previous reports, globin mRNA translation in oocytes results in a concomitant decrease in endogenous protein synthesis. In contrast, injection of adenovirus 5 mRNA into the oocyte results in a stimulation of endogenous protein synthesis. The stimulation is dose dependent and does not require nuclear transcription in the oocyte. Preliminary mapping data suggest that the stimulatory RNA is a product of one of the viral immediate early genes.
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