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  • 标题:Chromosomal localization of human leukocyte, fibroblast, and immune interferon genes by means of in situ hybridization
  • 本地全文:下载
  • 作者:Jeffrey M. Trent ; Sharon Olson ; Richard M. Lawn
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1982
  • 卷号:79
  • 期号:24
  • 页码:7809-7813
  • DOI:10.1073/pnas.79.24.7809
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Recombinant plasmids containing cDNA inserts from human leukocyte interferon (IFN-), fibroblast interferon (IFN-{beta}), or immune interferon (INF-{gamma}) genes were radiolabeled and hybridized in situ to human metaphase chromosome preparations. The results localized the human IFN- and IFN-{beta} genes to the short arm of chromosome 9(p21[->]pter) and localized the IFN-{gamma} gene to the long arm of chromosome 12(q24.1).
  • 关键词:human metaphase chromosomes
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