期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1983
卷号:80
期号:1
页码:129-132
DOI:10.1073/pnas.80.1.129
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:Standard midpoint potentials have been determined for p-benzoquinone, methoxy-p-benzoquinone and 2,3-, 2,5-, and 2,6-dimethoxy-p-benzoquinones in aqueous solution. ESR studies have been made of the ascorbate and semiquinone radicals produced when these quinones interact with sodium ascorbate. Direct correlations are found between the electrochemical potentials, generated semiquinone lifetimes, and cytotoxic action in Ehrlich ascites-bearing mice.