期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:1986
卷号:83
期号:3
页码:740-741
DOI:10.1073/pnas.83.3.740
语种:English
出版社:The National Academy of Sciences of the United States of America
摘要:In mice, pregnancy is often terminated when the stud male is removed and the pregnant female is exposed to the presence or scent of an unfamiliar male. It is reported here that the incidence of such blocking of pregnancy was higher when the stud and unfamiliar male differed by mutation of the H-2K class I gene of the major histocompatibility complex than when the stud and unfamiliar males were genetically identical. Thus, the olfactory distinction of mice differing by mutation of the H-2K gene, previously demonstrated after training of mice in a Y maze, can spontaneously influence neuroendocrine communications affecting reproduction.