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  • 标题:DNA Polymerase Activity Associated with RNA Tumor Viruses
  • 本地全文:下载
  • 作者:M. Hatanaka ; R. J. Huebner ; R. V. Gilden
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1970
  • 卷号:67
  • 期号:1
  • 页码:143-147
  • DOI:10.1073/pnas.67.1.143
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:C-type RNA viruses, originating in mouse, cat, hamster, and viper, catalyze the synthesis of DNA from its constituent deoxyribonucleoside triphosphates. Both the rate and extent of the reaction were significantly enhanced by brief treatment of the intact virus with ether. A proportion of the newly synthesized DNA was associated with virions when intact virus was used as template; this was not the case with ether-treated virus. In both cases, DNA extracted from the reaction mixture sedimented slowly, at about 2-4 S.
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