期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1970
卷号：67
期号：1
页码：164-171
DOI：10.1073/pnas.67.1.164
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：In crude homogenates of the submaxillary gland of the male mouse, epidermal growth factor (EGF) activity was found almost entirely in a high molecular weight complex (about 74,000 daltons). This high molecular weight form may be reversibly dissociated into EGF and an EGF-binding protein. EGF was found to have a molecular weight of approximately 6400. The EGF-binding protein has a molecular weight of 29,000, and shows arginyl-esterase activity.
