期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1970
卷号：67
期号：1
页码：193-199
DOI：10.1073/pnas.67.1.193
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Serum obtained from guinea pigs immunized with unfertilized C57BL/6 mouse eggs was found to be cytotoxic in the presence of complement for eggs obtained from syngeneic and allogeneic mice. The anti-egg serum was not cytotoxic for rat eggs, lymph node cells, methylcholanthrene-induced tumor cells, or 3T3 cells obtained either from syngeneic or allogeneic mice. The anti-egg serum was, however, cytotoxic for SV40-transformed 3T3 cells and C57BL/6 cells. After absorption with SV40-transformed cells, anti-egg serum lost its cytotoxicity for mouse eggs.
