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  • 标题:The Septate Junction: A Structural Basis for Intercellular Coupling
  • 本地全文:下载
  • 作者:Norton B. Gilula ; Daniel Branton ; Peter Satir
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1970
  • 卷号:67
  • 期号:1
  • 页码:213-220
  • DOI:10.1073/pnas.67.1.213
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:Electron microscopy, freeze-etching, and optical diffraction show how the structure of the septate junction may provide the basis for the low-resistance pathway between the electrically coupled cells in mussel gill epithelia. Conventional electron microscopy suggests that the septa are pleated sheets that differentiate from and are structurally continuous with the junctional cell membranes. Freeze-etching exposes geometrically arranged rows of 85-A particles within the junctional cell membranes. Diffraction evidence shows that these membrane particles and the alternate vertices of the intercellular septal sheets are congruent and therefore superposable. Together, the membrane particles and septal sheets provide a channel that extends from the cytoplasm of one cell through the septate junction to the cytoplasm of the adjacent cell.
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