期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1971
卷号：68
期号：5
页码：951-955
DOI：10.1073/pnas.68.5.951
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：A large (86S) glycoprotein isolated from rabbit seminal plasma acts on sperm cells to block fertilization. The proportion of fertilized eggs recovered from does 1 day after tubal insemination of sperm 5-6 hr before or 2-3 hr after ovulation was significantly depressed when uterine-capacitated spermatozoa were exposed to this substance at concentrations of 20-72 {micro}g of protein/ml. Rabbit seminal plasma was estimated to have about 2 mg/ml of this factor. Another large glycoprotein ([~]138S) is also present in rabbit seminal plasma; the function of this molecule awaits elucidation.
