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  • 标题:RNA-Dependent RNA Polymerase Activity in Influenza Virions
  • 本地全文:下载
  • 作者:Edward Penhoet ; Henry Miller ; Michael Doyle
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1971
  • 卷号:68
  • 期号:6
  • 页码:1369-1371
  • DOI:10.1073/pnas.68.6.1369
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:An RNA-dependent RNA polymerase activity has been detected in purified preparations of influenza virus. In contrast to the replicase activity induced in influenza-infected cells, the virion-associated enzyme has an absolute requirement for Mn++. Most of the RNA synthesized in vitro is complementary to virion RNA.
  • 关键词:eggs ; cell culture ; Mn++ requirement ; (NH4)2SO4 stimulation
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