期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1971
卷号：68
期号：9
页码：2165-2168
DOI：10.1073/pnas.68.9.2165
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：The effects of potential neurohormones on the intracellular concentrations of adenosine 3':5'-cyclic monophosphate have been examined with three clonal lines of cultured glial tumors. In all cases, norepinephrine and isoproterenol produced striking elevations of the intracellular concentrations of the cyclic nucleotide. The response was mediated by a {beta}-adrenergic receptor. This effect is hypothesized to represent a molecular mechanism for neuronal-glial communication coupled to concurrent communication between neurons.
关键词：neuron ; isoproterenol ; norepinephrine ; neuronal-glial communication
