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  • 标题:A Novel Closed-Circular Mitochondrial DNA with Properties of a Replicating Intermediate
  • 本地全文:下载
  • 作者:Harumi Kasamatsu ; Donald L. Robberson ; Jerome Vinograd
  • 期刊名称:Proceedings of the National Academy of Sciences
  • 印刷版ISSN:0027-8424
  • 电子版ISSN:1091-6490
  • 出版年度:1971
  • 卷号:68
  • 期号:9
  • 页码:2252-2257
  • DOI:10.1073/pnas.68.9.2252
  • 语种:English
  • 出版社:The National Academy of Sciences of the United States of America
  • 摘要:A fraction of the covalently closed mitochondrial DNA in mouse L cells contains a replicated heavy-strand segment that is hydrogen bonded to the circular light strand. The inserted single strand is dissociable from the circular duplex at an elevated temperature.
  • 关键词:density-gradient centrifugation ; electron microscopy ; separated strands ; ethidium bromide ; mouse DNA
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