期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：1971
卷号：68
期号：9
页码：2012-2015
DOI：10.1073/pnas.68.9.2012
语种：English
出版社：The National Academy of Sciences of the United States of America
摘要：Wild-type Phycomyces blakesleeanus accumulates {beta}-carotene, while the mutant strain C2 is unable to synthesize carotenoids, and the mutant strain C9 accumulates lycopene. Heterokaryons containing a proportion, p, of C2 nuclei and (l -- p) of C9 nuclei accumulate lycopene, {gamma}-carotene, and {beta}-carotene in the relative amounts (l -- p), p(l -- p), and p2, respectively, for different values of p. It is shown that these results are expected from the operation of a carotenogenic enzyme aggregate that works as an assembly line and contains two copies of a cyclase, which is defective in strain C9, as well as other enzymes.
